Information from this source is evidence-based and objective, and without commercial influence. J Pharmacopuncture 2021;24(4):196-205. D'Anchise, R., Bulitta, M., and Giannetti, B. Comfrey extract ointment in comparison to diclofenac gel in the treatment of acute unilateral ankle sprains (distortions). Comfrey contains chemicals called. Yield: Approximately 5 cups of whipped lotion. . Although it has historically been used on open wounds, it is now not advised related to the toxic pyrrolizidine alkaloids that can absorb more readily into the body through an open wound. The Herbal Academy neither endorses them nor is in any way responsible for their content. Copyright 1996-2023 Cerner Multum, Inc. 2013;163(3-4):58-64. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Roeder E. Medicinal plants in Europe containing pyrrolizidine alkaloids. Comfrey is not recommended for children under three years old, as it's not been studied in that population. All rights reserved. Knee pain and stiffness can be a stubborn concern that keeps many from doing activities they enjoy. Electric bowl mixer (like a KitchenAid) or a blender, Small glass jars with lids for sharing (optional). 2758955. Adv.Ther 2000;17(4):204-210. hollandandbarrett.ie is a trading name of Holland & Barrett Retail Limited. 2004;11(6):470-477. Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials. (2004). Verywell Health's content is for informational and educational purposes only. Acupuncture has also shown solid evidence of benefit for back pain. New South Wales Health, Australia. BMJ Case Rep. 2016. A later study of 133 peoplefound some evidence that a topical combination of comfrey extract and tannic acid led to reduced knee pain. As a Licensed Massage Therapist, I have personally made this comfrey cream recipe multiple times and given jars to my clients. It can grow up to 5 feet tall. While there can be a variety of causes for back pain, these small studies offer hopeful results that comfrey root may offer potential analgesic and anti-inflammatory benefits. 2012;20(11):1209-1216. The efficacy and safety of comfrey. Barna, M., Kucera, A., Hladikova, M., and Kucera, M. Randomized double-blind study: wound-healing effects of a Symphytum herb extract cream (Symphytumxuplandicum Nyman) in children. This includes androstenedione, bishop's weed, borage, chaparral, comfrey, DHEA, echinacea, garlic, germander, golden ragwort, hound's tongue, kava, licorice, niacin (vitamin B3), pennyroyal oil, red yeast, St. John's wort, and others. All rights reserved. Be sure to use comfrey root from a reputable source that has properly identified the species. View abstract. Comfrey is a plant also known as Ass Ear, Black Root, Blackwort, Bruisewort, Consolidae Radix, Consound, Consoude, Consuelda, Gum Plant, Healing Herb, Herbe aux Charpentiers, Herbe la Coupure, Knitback, Knitbone, Langue-de-Vache, Oreille d'ne, Salsify, Slippery Root, Symphytum officinale, or Wallwort. Join Rewards for Life today and we'll give you 300 points worth 3, Save 5% on your favourite products, plus get the lowest price from the last 90 days and free delivery on orders over 10. Efficacy of a comfrey root extract ointment in comparison to a Diclo-fenac gel in the treatment of ankle distortions: Results of an observer-blind, randomized, multicenter study. Comfrey oil should be applied topically to parts of the body where you have muscular pain or discomfort. randomized, placebo-controlled, double-blind, multi-clinical trial. Acupuncture for Chronic Pain: Update of an Individual Patient Data Meta-Analysis. (21), 498-507. https://link.springer.com/article/10.1007/s10354-004-0114-8, Natural Medicines (2020). 1 It's found in Europe, Asia, and North America. 2007;157(21-22):569-574. Complementary Health Approaches for Chronic Pain: What the Science Says. Avoid with medications that induce CYP3A4 or are hepatotoxic (Natural Medicines, 2020). Gyorik, S. and Stricker, H. Severe pulmonary hypertension possibly due to pyrrolizidine alkaloids in polyphytotherapy. 2023 Dotdash Media, Inc. All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Phytomedicine, 11(6), 470-477. https://doi.org/10.1016/j.phymed.2004.02.001, Kucera, A., Barna, M., Holcova, S., Horacek, O., Hladikov, M., & Ottillinger, B. Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: Results of a double-blind, randomised, placebo controlled, multicentre trial. Liver injury from herbal and dietary supplements. Registered office: Samuel Ryder House, Barling Way, Eliot Park, Nuneaton, CV10 7RH, UK. Follow all directions on the product label and package. This is because only a small amount of the pyrrolizidine alkaloids are absorbed through the skin (. Copyright Holland & Barrett Limited 2023. In a randomized, double-blind, placebo-controlled trial, 220 patients with knee osteoarthritis used either a commercial topical comfrey root extract or a placebo. Do not use this product if you have a sensitivity to any of the ingredients. Symphyti) in the treatment of ankle distorsions: Results of a multicenter, randomized, placebo-controlled, double-blind study. View abstract. Herbal drugs and phytopharmaceuticals. An ankle sprain can come out of nowhere and cause a lot of pain, limitations, and regret until it is healed. Complement Ther Clin Pract. The participants were assigned three weeks of treatment with two grams of either comfrey ointment or a placebo three times a day. Book your free, one-to-one online consultation with one of our qualified advisors. Inhibition of prostaglandin biosynthesis and PAF-induced exocytosis. Definitely do not use during pregnancy or nursing, with infants, and if you have liver or kidney disease. For that reason, Ive also included my go-to comfrey cream recipe for achy joints and muscles! International Journal of Pediatrics and Adolescent Medicine, 5(4), 135-141. https://doi.org/10.1016/j.ijpam.2018.11.002, Kuera, M., Barna, M., Horek, O., Kovrikov, J., & Kuera, A. Shop buy 1 get 1 half price on all gut health products, Buy 1 get 1 Half Price | Plus an extra 20% off 25, App Exclusive | Get an extra 22% off 25 when you spend on the H&B App, Royal Mail strikes may cause a delay to our click and collect service, Looking for fitness advice & inspiration this New Year? 2017;83:1-4. Not all possible interactions are listed in this product guide. Symphytum officinale), store bought or via recipe, above. Comfrey contains chemicals that can cause liver damage, lung problems, or cancer. Jurcu, R., & Jurcu, I. We go to great efforts to ensure that the information on this page is accurate at the time that the page was last edited. In a randomized multicenter study with 164 ankle sprain patients, swelling and pain were improved more successfully using a comfrey root extract compared to a diclofenac gel (Predel et al., 2005). Oral use of comfrey is not recommended because of potential liver damage. Comfrey ( Symphytum officinale) is an attractive ornamental plant used in gardening and medicine. Its ready when the mixture has solidified somewhat and has a cloudy, creamy, and slightly runny consistency. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. View abstract. Registered in England: company no. An Evidence-Based Reference. Comfrey is often sold as an herbal supplement. What Are the Side Effects of Comfrey Cream? Copyright Holland & Barrett Retail Limited, 2022. 1/8 cup comfrey tincture (Symphytum officinale), store bought or via recipe, above. 16 Rewards for Life points with this purchase. Cbd Oil In Holland And Barrett. 2012;20(11):1209-16. doi:10.1016/j.joca.2012.07.019, Zago LR, Prado K, Benedito VL, Pereira MM. Efficacy and tolerance of a comfrey root extract (Extr. Don't use comfrey products if you have or are at risk of having liver disease, cancer, or are taking any medication that affects the liver since it may increase the risk of liver toxicity. Turley, A. J. and Muir, D. F. ECG for physicians: a potentially fatal case of mistaken identity. Comfrey has also been used for the following conditions: There is currently not enough evidence to recommend comfrey cream for any of these uses. However, further well-designed studies are needed. Rad. Do not use this product without medical advice if you are pregnant. Documented adverse effects (the pyrrolizidine alkaloids, have substantial risk of causing fatal liver damage and can cause abortion). This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. 2758955. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. One study in 120 patients with acute upper or lower back pain used either four grams (g) of comfrey root ointment or a placebo (sham treatment) three times daily for five days. 2010;73(2):97-100. Choose a supplement tested by a trusted third party, such as USP, ConsumerLabs, or NSF when possible. Find out how to use it here along with its benefits. Anotherstudy found that comfrey ointment was superior to placebo in relieving pain and stiffness in osteoarthritis. Comfrey is traditionally used for the symptomatic treatment of minor sprains and bruises and is also known for its healing properties Customer Reviews Ingredients Full ingredients Brassica Campest is Seed Oil (Rapeseed Oil), Symphytum Officinale Herb (Comfrey Herb), BHA, Eucalyptus Globulus Leaf Oil (Eucalyptus Oil). The Herbal Academy supports trusted organizations with the use of affiliate links. Mei N, Guo L, Fu PP, Fuscoe JC, Luan Y, Chen T. Metabolism, genotoxicity, and carcinogenicity of comfrey. The review included one study of 220 people with knee osteoarthritis, a degenerative "wear-and-tear" joint condition. Choose organically grown comfrey when possible. In a small study with 30 subjects, lower back pain from exercise was reduced with an ointment containing comfrey. Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: results of a double-blind, randomised, placebo-controlled, multicentre trial. Registered VAT no. Squish and squeeze as many leaves into as you can into the container. Comfrey shouldn't be used in any form during pregnancy or nursing due to the risk of liver damage to infants. View abstract. Comfrey flowers are bell-shaped and purple, pink, or pale yellow in color, and it has a dark taproot. Those who used the comfrey ointment experienced improvements in pain, mobility, and quality of life. Label with the ingredients and date made. Smith, D. B., & Jacobson, B. H. (2011). Poisons Legislation Circular 3-22-1993;60. Barna, M., Kucera, A., Hladikova, M., & Kucera, M. (2012). Beth Thomas, PharmD, is a clinical pharmacist and founder of BMT Consulting Services, LLC. Published 2021 Sep 20. doi:10.1590/1519-6984.249209, Frost R, MacPherson H, O'Meara S. A critical scoping review of external uses of comfrey (Symphytum spp.). Molecules. Its long, lance-shaped leaves can be up to 1 foot in length closer to the bottom of the stem and are shorter higher up the stem. Written by Cerner Multum. You should never ingest comfrey by mouth. Phytother.Res 2012;26(10):1441-1448. Store comfrey cream according to package instructions, typically at room temperature and out of reach of children and pets. If your healthcare provider recommends it, make sure to use it on intact skin for a small amount of time, and be careful that infants do not ingest it. To make the cream, combine sunflower oil, safflower oil, coconut oil, and cocoa butter in a double-boiler over low heat until completely melted. Browse our Sports Hub, Get 20% student discount with Student Beans, Discover the latest natural beauty products. In Western Europe, comfrey has been used topically for treating inflammatory disorders such as arthritis, gout, and thrombophlebitis, and internally for treating diarrhea. Wien Med Wochenschr. Ministry of Environment & Forests, Govt. No comments. Supplements marketed for body-building (ex.. Acupuncture for Chronic Pain: Update of an Individual Patient Data Meta-Analysis. Efficacy of a comfrey root extract ointment in comparison to a Diclo-fenac gel in the treatment of ankle distortions: Results of an observer-blind, randomized, multicenter study. Using a combination product makes it challenging to know how much of the beneficial effect came from comfrey alone. Call your doctor if the condition you are treating with comfrey does not improve, or if it gets worse while using this product. Safety Alerts & Advisories: FDA Advises Dietary Supplement Manufacturers to Remove Comfrey Products From the Market. The Comfrey Controversy: Can and Should One Use Comfrey Internally? Staiger, C. Comfrey root: from tradition to modern clinical trials. Osteoarthritis Cartilage. 20 Rewards for Life points with this purchase, Potters Herbals Comfrey Ointment is a traditional herbal medicinal product used for the symptomatic relief of minor sprains and bruises, based on traditional use only. Quis autem velum iure reprehe nderit. This is done by soaking the root in at least 50% alcohol for a minimum of two weeks. Thus, it is not advised to ingest herbal preparations of comfrey unless guided by an expert pharmacologist and physician. Regulatory Toxicology and Pharmacology, 83, 1-4. https://doi.org/10.1016/j.yrtph.2016.11.015. This site uses cookies to improve your experience. Allow the oil mixture to cool until it reaches room temperature, which could take 8-12 hours. We comply with the HONcode standard for trustworthy health information. It's found in Europe, Asia, and North America. Discontinue use if a rash appears. The comfrey plant, Symphytum officinale, gets its name from the Latin confervere, meaning to grow together. Predel, H. G., Giannetti, B., Koll, R., Bulitta, M., & Staiger, C. (2005). Hybrids and other species may have a similar appearance but could have significantly different amounts of the toxic pyrrolizidine alkaloids (Kucera et al., 2018). Comfrey root: from tradition to modern clinical trials, Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: results of a double-blind, randomised, placebo-controlled, multicentre trial, Topical herbal therapies for treating osteoarthritis, Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials, Treatment with 4Jointz reduces knee pain over 12 weeks of treatment in patients with clinical knee osteoarthritis: a randomised controlled trial. Pharmazie 1995;50:83-98. Set aside cup for the cream recipe and store the rest in a glass jar. WebMD does not provide medical advice, diagnosis or treatment. View abstract. Comfrey is generally considered unsafe, with numerous toxicological effects in animals and humans. It contains chemicals that are poisonous. (3), 147-156. https://doi.org/10.1016/j.jcm.2011.01.003. Rad. radix) extract ointment in the treatment of patients with painful osteoarthritis of the knee: results of a double-blind, randomised, bicenter, placebo-controlled trial. Can comfrey be used for cracked nipples during breastfeeding? Mix for about 10 minutes, until nice and whipped. For topical comfrey cream, look for products labeled as free of pyrrolizidine alkaloids. Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: Results of a double-blind, randomised, placebo controlled, multicentre trial. By Megan Nunn, PharmD Consult with a licensed healthcare professional before using any herbal/health supplement. Please review this supplement label with your healthcare provider to discuss potential interactions with foods, other supplements, and medications. Bleakley, C. M., McDonough, S. M., and MacAuley, D. C. Some conservative strategies are effective when added to controlled mobilisation with external support after acute ankle sprain: a systematic review. Hepatology. 1. Lewis, C. J. FDA Advises Dietary Supplement Manufacturers to Remove Comfrey Products From the Market. Please read the Topical Use Safety section of this article (above) before using. Barna, M., Kucera, A., Hladikova, M., & Kucera, M. (2012). Efficacy and tolerance of a comfrey root extract (Extr. Influence of moderate physical exertion on subacute low back pain, after Symphytum officinale ointment treatment. Be sure to choose organic carrier oils and essential oils when possible. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. To make this recipe, first, you must prepare the comfrey root tincture. The ankle swelling decreased by 79.5% in the comfrey root group and 69.4% in the diclofenac group. Here's 10 things essential oils are great for. Comfrey might harm the liver. J Pharm.Belg. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. 4.3 4.3 out of 5 stars (225) $19.95 $ 19. Avila C, Breakspear I, Hawrelak J, Salmond S, Evans S. A systematic review and quality assessment of case reports of adverse events for borage (Borago officinalis), coltsfoot (Tussilago farfara) and comfrey (Symphytum officinale). Select a condition to view a list of vitamins. Retrieved from https://naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=295, Predel, H. G., Giannetti, B., Koll, R., Bulitta, M., & Staiger, C. (2005). root extraction help ease aching joints and muscles? This makes quite a thick rich cream good for a body cream and an all healing cream . Herbal drugs and phytopharmaceuticals. MedlinePlus Medical Encyclopedia. J Ethnopharmacol 1995;48(2):61-76. Comfrey has long been used in folk traditions for bruising and abrasions. You may also consider consulting a practitioner who is trained in the use of herbal/health supplements. Many of those following the folk use of comfrey up to present-day think so. 2014;20(4):347-55. Ingesting cooking oil has been banned by the European Union, due to a high risk of liver toxicity.9, Adults with liver disease, cancer, or a history of alcoholism are also advised to avoid comfrey because the skin can also absorb the liver-damaging compounds. View abstract. When the root is boiled in water, it forms a sticky, glue-like paste. J Chiropr Med. First, make the comfrey root tincture by combining the dried comfrey root and alcohol in a sterilized, dry, glass pint jar. Proliferative and antioxidant activity of Symphytum officinale root extract. They help us to understand how people use the website and give us the ability to provide targeted marketing to you. Comfrey should not be used in place of medication prescribed for you by your doctor. 2013;5(5):CD010538. how to become a school board member in florida ocean deck band schedule The chemicals contained in comfrey may cause birth defects. July 6, 2001. hollandandbarrett.com is a trading name of Holland & Barrett Retail Limited,. Since these toxic substances can be absorbed through the skin, there's concern about the safety of comfrey cream applied topically. comfrey cream holland and barrett. One group used a cream with comfrey root fluid extract on the ankle while the others received a placebo. Cap, then label the jars with the date made and ingredients. NCCIH. This comfrey cream recipe works great for local areas that have mild bruising or soft tissue pain. Stam, C., Bonnet, M. S., & van Haselen, R. A. One study followed 142 patients with ankle sprains. Comfrey cream combines ingredients like oils or water and glyceryl stearate with Symphytum officinale (comfrey) extracts. 1.35 Fl Oz. Spine(Phila Pa 1976). Whether youre familiar with it or not, this unusual herbal remedy is definitely worth knowing more about. 2010;13(7-8):509-526. doi:10.1080/10937404.2010.509013, Staiger C. Comfrey: A clinical overview. Facebook; Twitter; Pinterest; Related Posts. For one of these studies, the average time participants had experienced knee pain and stiffness leading up to the study was six and a half years! Ask a doctor, pharmacist, or other healthcare provider if it is safe for you to use this product if you have: Comfrey is considered likely unsafe to use during pregnancy. Medicine makers would bind comfrey leaves and roots in poultices, then apply those poultices to the skin to treat injuries. Drugs and Lactation Database (LactMed). Its long, lance-shaped leaves can be up to 1 foot in length closer to the bottom of the stem and are shorter higher up the stem. radix) extract ointment in the treatment of patients with painful osteoarthritis of the knee: Results of a double-blind, randomised, bicenter, placebo-controlled trial. Huxtable RJ, Awang DV. Registered in England: company no.
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